Mimicking a single cell 바카라 사이트: From lipid membranes to extracellul…

It is very difficult to define “how a living organism maintains its life”, due to its vast complex disciplines, including its 바카라 사이트, function, growth, origin, and evolution. However, there are many progresses in cell biology, by narrowing the target to an individual cell, which is a building block to compose all living things. Therefore, mimicking structural and functional “artificial cells” can open a new horizon in biophysics, since a cell is also considered to be the basic unit in many pathological processes. Current achievements of researches in mimicking cellular 바카라 사이트s are including 1) assembling cellular membranes, composed of mainly phospholipids, and 2) determining the cytoplasmic skeletons, and it will provide a key information to produce, at least, physically (visoelastically controlled) and chemically (lipid based) controlled cellular vesicles when those 바카라 사이트s are combined into a single 바카라 사이트. Another important step to produce “artificial cells” is how we can produce cellular organelles (i.e. mitochondria, ribosomes, Golgi, nucleus, etc) in a plasma cellular vesicle. Not like a cell membrane, mostly having a spherical 바카라 사이트, 바카라 사이트s of cellular organelles varies greatly, but uniquely. While a nucleus and many vesicles have a spherical shape, ERs have an interconnected network 바카라 사이트 of tubules and vesicles. A mammalian mitochondrion has a double membrane 바카라 사이트 (elongated vesicle-like outer membrane and ruptured and folded inner membrane). In this study, we would like to find a way to produce bio-mimetic lipid membrane 바카라 사이트s, aiming to create a single cellular boundary. Then, we could insert various components which are mostly providing cellular functions and 바카라 사이트s. We will introduce how we can build up a simple lipid membranes to functionalized complex membrane, and by addition of extra-, intracellular proteins, we could build an artificial cellular 바카라 사이트s, mimicking a living cellular 바카라 사이트s, physically and functionally.